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Our Research

At SONLab, we're pushing the boundaries of cellular signaling and molecular dynamics through cutting-edge research. Our work focuses on understanding the intricate mechanisms of protein-protein interactions and developing innovative tools to study them.

Regulation of Raf Activity by KRas Dimerization

Investigating the fundamental mechanism of Raf activation, specifically examining whether KRas homodimerization is essential or if monomeric KRas can drive downstream signaling. Our research explores KRas-Gα heterodimerization and the impact of various KRas mutations on signaling outcomes in cancer and neuronal contexts.

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K-Ras/G-alpha Heterodimerization Effects

Exploring the controversial mechanism of Raf activation by K-Ras, with a focus on the potential role of K-Ras forming heterodimers with Gα proteins. This research aims to resolve key controversies in cell signaling and uncover novel regulatory mechanisms with implications for cancer biology and neurology.

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Microscope Automation & Image Analysis

Developing standardized autonomous control systems for confocal microscopes and creating in-house Python software for automated image acquisition and processing. This project aims to eliminate human error and improve efficiency in molecular interaction studies through advanced automation and machine learning.

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Tools & Resources

We build and openly share the software behind our research — analysis tools and platforms developed in-house and free for the scientific community.

FRET Analysis Tool

A high-throughput, open-source application for analyzing Förster Resonance Energy Transfer (FRET) data with advanced image processing — open for free public use.

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Docking Platform Dashboard

An interactive dashboard for our molecular docking and drug-screening campaigns — explore poses, scores, and validation results across the disease models we investigate.

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