Thesis Research

Investigating the significance of α-interface hot spots on K-Ras homodimer formation

The role of G-domain on K-Ras and Gα dimerization

Investigating the homo-dimerization of ADGRD1/GPR133 and ADGRG5/GPR114 via resonance energy transfer techniques

Detection of the homo-oligomerization of ADGRE2/EMR2 using BRET and FRET

Fluorescent labeling of SPOCK1 and localization studies in live neural cell lines

Development of a composite guide for peripheral nerve regeneration

The effect of topography-induced mechanotransduction on expression levels of focal adhesion-related genes in neuro-2A cells

The effect of BFPP mutations on trafficking, signaling and function of ADGRG1/GPR56 receptor

Investigation of the effect of GPCR oligomerization on the GNAI1 homodimerization in live cells using FRET

Aptamer selection against cadaverine/lysine antiporter (CADB) purified in mild detergent

Systematic evolution of novel 2′F-PY RNA aptamers targeting the membrane protein l-arginine/agmatine antiporter purified in mild detergent

A brighter method to illuminate the dark side of adhesion g protein-coupled receptors: detection of the ADGRG1 dimers by bioluminescence resonance energy transfer (BRET)

Investigation of physical interaction between gαi and gαs proteins via FRET in live cells

Phosphorylation independent activation of beta arrestin 2 and beta adrenoceptor type 2 by means of small molecules

Behavior of neuro-2a cells on femtosecond laser structured silicon substrates

Analysis of interactions between beta-2 adrenergic receptor & beta arrestin-2 using förster resonance energy transfer (fret) method in live cells

Prediction of transmembrane regions of g protein-coupled receptors using machine learning techniques

Investigation of gαi1 protein homodimerization in live cells using förster resonance energy transfer (FRET) and bimolecular fluorescence complementation assay (BiFC)

Visualization of interactions between fluorescently tagged G protein α11, α12/13 subtypes and adenosine 2A, dopamine 2 or homodimer adenosine 2A/2A receptors

Nucleic acid gated nanopore delivery of antibiotics

Nucleic acid based in-vitro diagnostic device

Molecular investigation of therapeutical effects of ɣ-tocotrienol conjugation therapy with doxorubicin on hepatocellular carcinoma cell line HEPG2

Optimization of internal tagging of inhibitory G-proteins for investigating their interactions with dopamine receptor D2 via fret method

More than just a dimer: detection of g protein-coupled receptor oligomers using fluorescent protein reassembly of Ste2p, a yeast pheromone receptor

Design and characterization of 5-L autoclavable batch-culture bioreactor

In vivo detection of GPCR dimerizations in Saccharomyces cerevisiae using FRET and BiFC

In vivo detection of yeast alpha mating pheromone receptor Ste2p homodimerization by FRET

Identifying the putative G protein coupled receptor/s candidates of cocaine and amphetamine regulated transcript (CART) peptide

Detection of homo/hetero-dimerizations between adenosine A2A, dopamine D2 and NMDA receptors by use of FRET and BiFC assays

In vivo detection of GPCR dimerizations in Saccharomyces cerevisiae using FRET and BiFC

Labeling and optimization of organelle marker for co-localization with yeast GPCR dimers

Comparison of fluorescent protein labelled and wild type NMDA receptor distribution

The functional assessment of fluorecently tagged adenosine a2a and dopamine D2 receptors and qualitative analysis of dimerization of adenosine A2A and dopamine D2 receptor by using fret

Detecting g-protein coupled receptor interactions using enhanced green fluorescent protein reassembly

Optimization o fret method to detect dimerization of dopamin D2 and adenosine A2A receptors in live cells